Lasilactone 100/20 mg 30 tablets

Available at Pharmaegy Pharmacy. Use as directed by your doctor.

Trade Name: Lasilactone Composition: Each tablet contains: Spironolactone 100 mg Furosemide 20 mg Inactive ingredients: Lactose monohydrate, starch, povidone, talc, magnesium stearate, macrogol. Properties: Combined drug, the action of which is due to the components that make up its composition; has a diuretic and hypotensive effect. Furosemide is a “loop” diuretic; causes a rapidly advancing, strong and short-term diuresis. It has a natriuretic, choleretic effect, and increases the excretion of K+, Ca2+ and Mg2+. Spironolactone competitively blocks the binding of aldosterone to its cytoplasmic receptor in the terminal part of the distal convoluted tubule and in the collecting tubule; reduces the reabsorption of Na + and has a potassium-sparing effect. Leads to mild acidosis due to H+ retention. Indications: Edema and ascites in violation of electrolyte metabolism due to hyperaldosteronism and in case of insufficiency of previous treatment with diuretics; CHF; ascites due to liver failure; nephrotic syndrome. Dosage and administration: inside. In the first 3-6 days – 1 capsule 4 times a day; maintenance dose – 1 capsule 1-3 times a day or every second or third day. Capsules should be swallowed without chewing, with sufficient liquid. Contraindications: Hypersensitivity, anuria, acute renal failure (CC less than 30 ml / min or serum creatinine concentration above 1.8 mg / dl), hypokalemia, hypovolemia with or without concomitant arterial hypotension, pregnancy, hepatic precoma and coma. With caution.Hyperplasia of the prostate. Warnings and precautions: Regular monitoring of electrolytes in the blood serum (primarily K + and Na +), urea in the blood serum, CBS is necessary. In chronic renal failure with CC below 60 ml / min or serum creatinine concentration above 1.5 mg / dl, it is necessary that the drug be treated only with frequent monitoring of serum K + concentrations. The decrease in body weight caused by increased diuresis should not exceed 1 kg per Side effects: Violation of water and electrolyte metabolism, hyperkalemia, hypokalemia, hyponatremia, hypovolemia, loss of appetite, dry mouth, thirst, impaired acid-base balance, headache, weakness, dizziness, drowsiness, cramps in the calf muscles, decreased blood pressure, blurred vision, dehydration, thrombosis, myasthenia gravis, hypercalcemia, nausea, vomiting, constipation or diarrhea, nephrocalcinosis (in newborns); acute urinary retention (with prostatic hypertrophy); hyperglycemia, hypercholesterolemia, hypertriglyceridemia. Increased tactile sensitivity of the nipples of the mammary gland, gynecomastia, mastodynia, hoarseness, lowering the pitch of the voice in women and increasing in men; hirsutism, decreased potency. allergic reactions; hemolytic anemia, leukopenia, agranulocytosis, thrombocytopenia, eosinophilia, acute pancreatitis. day (regardless of the amount of urine excreted). Storage: Store at a temperature not exceeding 30°C. Package: The carton box contains 30 tablets, paper leaflet.