Xilopred 16 mg 20 tablets

Available at Pharmaegy Pharmacy. Use as directed by your doctor.

Xilopred 16 mg 20 tablets Active ingredient: Methylprednisolone — 16 mg. Description: Synthetic glucocorticosteroid with anti-inflammatory, immunosuppressive, and anti-allergic effects. Used for conditions requiring systemic hormonal therapy. Indications: - Endocrine disorders: adrenal insufficiency, congenital adrenal hyperplasia. - Rheumatic diseases: rheumatoid arthritis, juvenile arthritis. - Autoimmune diseases: systemic lupus erythematosus, dermatomyositis. - Allergic conditions: severe rhinitis, bronchial asthma, serum sickness. - Skin diseases: pemphigus vulgaris. - Hematological disorders: idiopathic thrombocytopenic purpura. - Neoplasms: leukemias, lymphomas. - GI diseases: ulcerative colitis, Crohn's disease. - Other: sarcoidosis, tuberculous meningitis (with anti-TB therapy). Dosage and Administration: - Initial dose depends on the disease (see table in leaflet). - Maintenance dose: minimal effective, taken once in the morning or every other day. - Withdrawal: gradual, under medical supervision. - Children and elderly: use with caution, minimal effective dose. Examples: Rheumatoid arthritis: 4–16 mg/day. Systemic lupus: 20–100 mg/day. Bronchial asthma: up to 64 mg/day. Contraindications: - Systemic fungal infections. - Hypersensitivity to methylprednisolone or excipients. - Live vaccination during immunosuppression. - Severe infections without specific therapy. Precautions: - Infections: Increased susceptibility to bacterial, viral, fungal infections. - Endocrine effects: Adrenal suppression, Cushing's syndrome. - GI: Ulcers, perforation, pancreatitis. - Cardiovascular: Hypertension, thrombosis. - Nervous system: Psychiatric reactions (depression, mania). - Ophthalmology: Cataracts, glaucoma. - Metabolism: Hyperglycemia, hypokalemia. - Bones: Osteoporosis (especially in postmenopausal women). Adverse Effects: Common (>1%): Sleep disturbances, weight gain, edema. Dyspepsia, hyperglycemia. Rare (<0.1%): Thrombosis, osteoporosis, psychiatric reactions. Cataracts, glaucoma. Long-term use: Adrenal insufficiency. Pregnancy and Lactation: Pregnancy: Only if strictly indicated (risk of fetal growth retardation). Lactation: Excreted in breast milk (use with caution). Storage: Store below 30°C in a dry place. Package: Carton box containing 2 blisters of 10 tablets.