Itopride 50 mg 30 tablets
Available at Pharmaegy Pharmacy. Use as directed by your doctor.
Itopride 50 mg Gastroprokinetic Agent 30 Tablets Description: Itopride 50 mg is an oral gastroprokinetic medication containing itopride hydrochloride — a benzamide derivative with a dual mechanism of action: dopamine D2 receptor antagonist and acetylcholinesterase inhibitor. It increases acetylcholine activity, improving gastrointestinal motility, accelerating gastric emptying, and enhancing coordination in the upper GI tract. It also has an antiemetic effect by acting on D2 receptors in the chemoreceptor trigger zone. Pharmacological Action: Stimulates gastric motility Increases lower esophageal sphincter tone Accelerates gastric emptying Improves gastroduodenal coordination Provides antiemetic action Does not affect serum gastrin levels Clinical studies confirm effectiveness in functional dyspepsia. Indications for Use: Treatment of symptoms related to impaired gastric motility and delayed gastric emptying: Bloating Early satiety Feeling of fullness after meals Pain or discomfort in the upper abdomen Loss of appetite Heartburn Nausea and vomiting Functional (non-ulcer) dyspepsia Chronic gastritis. Dosage and Administration: Adults: Recommended daily dose: 150 mg One tablet (50 mg) three times daily before meals Dosage may be adjusted depending on age and symptom severity Treatment duration: up to 8 weeks. Contraindications: Hypersensitivity to itopride or any components of the drug Conditions where increased GI motility is dangerous: Gastrointestinal bleeding Mechanical obstruction GI perforation. Precautions and Warnings: May cause cholinergic side effects due to increased acetylcholine activity Contains lactose; not recommended for patients with: Hereditary galactose intolerance Lapp lactase deficiency Glucose-galactose malabsorption syndrome. Side Effects: Common: GI: Abdominal pain, diarrhea Nervous system: Dizziness, headache. Uncommon: GI: Increased salivation Skin: Rash Laboratory tests: Elevated ALT, decreased leukocyte count. Post-marketing data (frequency unknown): Blood: Leukopenia, thrombocytopenia Immune system: Hypersensitivity, anaphylactoid reactions Endocrine system: Increased prolactin levels GI: Constipation, nausea, increased salivation Liver: Jaundice, elevated liver enzymes Skin: Erythema, itching Reproductive system: Gynecomastia Laboratory tests: Elevated AST, ALT, GGT, ALP, bilirubin. Storage Conditions: Store at temperatures not exceeding 30°C Protect from moisture; keep in a dry place. Packaging: Cardboard box containing 3 blisters of 10 tablets each and an instruction leaflet.
