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Estikan 20 mg, 14 tablets

Available at Pharmaegy Pharmacy. Use as directed by your doctor.

Properties: Escitalopram is an antidepressant, a selective serotonin reuptake inhibitor (SSRI) with high affinity for the active primary center. Escitalopram also binds to the allosteric center of the serotonin transporter protein with a 1000-fold lower affinity. Allosteric modulation of the transporter protein enhances the binding of escitalopram at the primary binding site, resulting in more complete inhibition of serotonin reuptake. Escitalopram has no or very weak ability to bind to a number of receptors including: serotonin 5-HT1A, 5-HT2 receptors, dopamine D1- and D2-receptors, α1-, α2-, β-adrenergic receptors, histamine H1-, muscarinic cholinergic, benzodiazepine and opiate receptors. Inhibition of 5-NT reuptake is the only possible mechanism of action that accounts for the pharmacologic and clinical effects of escitalopram. Escitalopram is the S-enantiomer of racemic citalopram with intrinsic therapeutic activity. The R-enantiomer has been shown not to be inert but to counteract the serotonergic properties and corresponding pharmacological effects of the S-enantiomer.

Estikan 20 mg, 14 tablets


Description

Properties: Escitalopram is an antidepressant, a selective serotonin reuptake inhibitor (SSRI) with high affinity for the active primary center. Escitalopram also binds to the allosteric center of the serotonin transporter protein with a 1000-fold lower affinity. Allosteric modulation of the transporter protein enhances the binding of escitalopram at the primary binding site, resulting in more complete inhibition of serotonin reuptake. Escitalopram has no or very weak ability to bind to a number of receptors including: serotonin 5-HT1A, 5-HT2 receptors, dopamine D1- and D2-receptors, α1-, α2-, β-adrenergic receptors, histamine H1-, muscarinic cholinergic, benzodiazepine and opiate receptors. Inhibition of 5-NT reuptake is the only possible mechanism of action that accounts for the pharmacologic and clinical effects of escitalopram. Escitalopram is the S-enantiomer of racemic citalopram with intrinsic therapeutic activity. The R-enantiomer has been shown not to be inert but to counteract the serotonergic properties and corresponding pharmacological effects of the S-enantiomer.

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Estikan 20 mg, 14 tablets

EGP 106.00 EGP 145.22 27% off

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