Trental SR 400 mg 20 tablets

Available at Pharmaegy Pharmacy. Use as directed by your doctor.

Tradename: Trental SR Trental SR Composition: Each tablet contains: Pentoxifylline 400 mg Auxiliary components: Hydroxyethyl cellulose, talc, magnesium stearate, sucrose, titanium dioxide, propylene glycol. Properties: Vasodilator. Pentoxifylline improves microcirculation and blood rheological properties. The mechanism of action of pentoxifylline is associated with inhibition of phosphodiesterase and the accumulation of cyclic AMP in the cells of vascular smooth muscle and blood cells. Pentoxifylline inhibits the aggregation of platelets and erythrocytes, increases their elasticity, reduces the level of fibrinogen in plasma and enhances fibrinolysis, which reduces blood viscosity and improves its rheological properties. It has a weak myotropic vasodilator effect. Pentoxifylline slightly reduces the total peripheral resistance and slightly dilates the coronary vessels. In general, Trental improves microcirculation and oxygen supply to tissues in the central nervous system and in the extremities, to a lesser extent in the kidneys. Indications: – Peripheral circulation disorders caused by atherosclerosis, diabetes mellitus (diabetic angiopathy), inflammation; – acute and chronic ischemic cerebral circulation disorders; – atherosclerotic and discirculatory encephalopathy; -angioneuropathy (paresthesia, Raynaud’s disease); – trophic tissue disorders due to impaired arterial or venous microcirculation (trophic ulcers, post-thrombophlebic syndrome, frostbite, gangrene); – obliterating endarteritis; -Acute, subacute and chronic circulatory failure in the retina or in the choroid of the eye; – hearing impairment of vascular origin. Method of administration and dosage: The duration of treatment and the dosage regimen of Trental are set by the attending physician individually, depending on the clinical picture of the disease and the therapeutic effect obtained. The drug is taken orally immediately after a meal, without chewing, with a sufficient amount of liquid. For adults, the drug is prescribed 400 mg 2-3 times / day. The course of treatment is 2-3 weeks or more. Contraindications: – acute myocardial infarction; – massive bleeding; – acute hemorrhagic stroke; – severe coronary or cerebral atherosclerosis; -severe heart rhythm disturbances; – hemorrhages in the retina; -pregnancy and lactation period; – age up to 18 years; -increased sensitivity to pentoxifylline, other methylxanthines or other components of the finished dosage form. Precautionary measures: Care should be taken when prescribing Trental to patients with gastric ulcer and duodenal ulcer, patients who have recently undergone surgery (risk of bleeding). Patients with labile arterial pressure and with a tendency to arterial hypotension and patients with severe renal impairment, the dose is gradually increased and selected individually. Side effects: Most often, when taking Trental, adverse events from the gastrointestinal tract may appear (nausea, a feeling of fullness in the abdomen, stomach cramps, vomiting, diarrhea). Dizziness and headache may sometimes occur. Occasionally, you can observe a decrease in blood pressure, angina pectoris, an abnormal heart rhythm, a feeling of flushing. Storage method: Store at a temperature not exceeding 25 degrees. In a place protected from light. Package: The cardboard box contains 2 blisters of 10 tablets, paper instructions.