Depakine Chrono 500 mg 30 tablets
Available at Pharmaegy Pharmacy. Use as directed by your doctor.
Tradename:
Depakine chrono
Depakine Chrono
Composition:
Each tablet contains:
333mg sodium valproate.
145mg valproic acid
Auxiliary components:
silicon dioxide, hypromellose, ethylcellulose, sodium saccharinate, colloidal silicon dioxide, Opadray II white, polyvinyl alcohol, macrogol, talc, titanium dioxide.
Properties:
Antiepileptic drug. It is believed that the mechanism of action is associated with an increase in the content of GABA in the central nervous system, which is due to inhibition of GABA transaminase, as well as a decrease in the reuptake of GABA in brain tissues. This, apparently, leads to a decrease in the excitability and convulsive readiness of the motor zones of the brain. It helps to improve the mental state and mood of patients.
Indications:
Epileptic seizures: generalized, focal (focal, partial) with simple and complex symptoms, small. Convulsive syndrome in organic brain diseases.
Method of administration and dosage:
The method of application and dosage regimen of a particular drug depends on its form of release and other factors. The optimal dosage regimen is determined by the doctor. It is necessary to strictly observe the compliance of the used dosage form of a particular drug with the indications for use and the dosage regimen.
The average daily dose is 1-2 doses per day with meals. Do not stop using the tablets without consulting your doctor.
Contraindications:
Severe liver dysfunction; severe dysfunction of the pancreas; porphyria; hemorrhagic diathesis; severe thrombocytopenia; I trimester of pregnancy; lactation (breastfeeding); hypersensitivity to valproic acid.
Precautionary measures:
It is used with caution in patients with pathological changes in the blood, with organic brain diseases, a history of liver disease, hypoproteinemia, and impaired renal function.
Side effects:
From the side of the central nervous system: trembling of the hands or arms is possible; rarely – changes in behavior, mood or mental state, diplopia, nystagmus, spots before the eyes, impaired coordination of movements, dizziness, drowsiness, headache, unusual agitation, restlessness or irritability.
On the part of the digestive system: mild cramps in the abdomen or in the stomach, loss of appetite, diarrhea, indigestion, nausea, vomiting are possible; rarely – constipation, pancreatitis.
On the part of the blood coagulation system: thrombocytopenia, prolonged bleeding time.
From the side of metabolism: an unusual decrease or increase in body weight.
On the part of the gynecological status: menstrual irregularities.
Dermatological reactions: alopecia.
Allergic reactions: skin rash.
Storage method:
in a cool dry place at a temperature not exceeding 25 degrees.
Package:
The cardboard box holds 30,40 or 100 tablets.